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KMID : 1007520100190010248
Food Science and Biotechnology
2010 Volume.19 No. 1 p.248 ~ p.252
Effect of Grape Seed Oil Supplementation on Plasma Lipid Profiles in Rats
Kim Dae-Jung

Jeon Geon-uk
Sung Jee-Hye
Oh Sea-Kwan
Hong Ha-Cheol
Lee Jun-Soo
Abstract
The purpose of the study was to investigate the comparative effects of feeding of grape seed oil (GSO), soybean oil (SO), and lard on plasma lipid profile in rats. Lard fed diets increased body weight gain in rats and resulted in negative effects on lipoprotein metabolism. However, the GSO fed rats had a significant reduction in total cholesterol (TC, 60.6 mg/dL), low density lipoprotein cholesterol (LDLC, 16.8 mg/dL), and atherogenic index (AI, 0.9), and the ratio of high density lipoprotein cholesterol (HDLC) to TC (0.5) was significantly higher than those of SO and lard groups. These data suggest that GSO supplementation has significant health benefits through favorable alterations in plasma lipid profiles compared to SO and lard fed rats. GSO may be good dietary oil and may provide health benefits in hyperlipidemia and related complications.
KEYWORD
grape seed oil, lipid profile, rat, soybean oil, lard
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